On a molecular level, retinol and retinoids are pure forms of Vitamin A, and are recognised by cellular receptors within the skin. Vitamin A plays an important role in controlling skin keratinization, an acceleration of cell growth and an activation of cell division. It is also necessary for the normal division of basal cells of the epidermis as it produces an increase in mitotic activity, resulting in improved epithelium renewal. Corresponding histological observations are a thickening of the epidermis and more precisely the Malpighian layer with an increasing amount of keratinocyte and corneocyte layers.


During intrinsic ageing, cellular turnover decreases by around 30%. Furthermore, dermal macromolecule production, such as collagen, elastin, glycosaminoglycans and proteoglycans, decreases strongly. Macroscopic manifestation of this natural phenomena includes dryness and wrinkling. As retinol enhances skin functioning and viability, it has long since been touted as a superior ingredient in the fight against skin ageing.


Research Scientists have worked for years on different types of retinoids. Many studies have shown that retinol can significantly improve skin texture, pore size, hyperpigmentation, skin clarity, fine wrinkling and photo damage. This ingredient however, does come with one drawback, and that is potential skin redness, irritation and flaking.


New science and technology has emerged with the development of Cylasphere™ Retinol an innovative and revered way to deliver vitamin A into the skin, bypassing the redness and flakiness which was normal with the use of Retin-A. Cylasphere™ Retinol makes use of Agar microspheres that enable the encapsulation of fragile retinol. These microspheres progressively open by the activity of many different skin enzymes, and gradually release retinol into the dermis. This slow membrane digestion leads to a slow release of encapsulated retinol, allowing for a better bio-availability, a better efficacy and a gentler use. Find this new and exciting Vitamin A form within the DermaFix ACC Retinol +, new from DermaFix Cosmeceutical Skin Care.


DermaFix ACC Retinol + increases moisture content of the skin whilst significantly improving skin’s radiance through an increase in blood flow to the skin.


Production of Collagen and Elastin improves and one can expect to see a considerable reduction of fine lines and wrinkles in approximately 3 months of regular use. DermaFix Cosmeceutical Skin Care is very proud of this amazing discovery, especially in the highly competitive world of skin care, with many products claiming to contain Retinol not working as well they should. DermaFix prides itself on offering result-driven products at a competitive price.


Due to the content of Retinol, DermaFix ACC Retinol + should only be used at night according to recommendation by a DermaFix Skin Care Professional. Daily protection against harmful UV radiation with DermaFix Ferulic + C + E and DermaFix DermaShield SPF40 / SPF50 High Protection Sunscreen is imperative. Monthly skin boosting protocols can be incorporated alongside home-use of this product, including advanced facial protocols like Microneedling.


DermaFix ACC Retinol + differs from the MD Prescriptives Vitamin A Propionate, in that it also includes Vitamin C for additional antioxidant and skin brightening benefits.